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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STK25
All Species:
15.15
Human Site:
S299
Identified Species:
27.78
UniProt:
O00506
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.5
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00506
NP_006365.2
426
48112
S299
S
E
G
H
G
E
E
S
S
S
E
D
S
D
I
Chimpanzee
Pan troglodytes
XP_001162228
584
64501
S457
S
E
G
H
G
E
E
S
S
S
E
D
S
D
I
Rhesus Macaque
Macaca mulatta
A4K2T0
487
55587
R310
K
R
Q
E
S
Q
Q
R
E
V
D
Q
D
D
E
Dog
Lupus familis
XP_848578
318
35396
K194
T
E
L
I
D
R
Y
K
R
W
K
S
E
G
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2W1
426
48157
S299
S
E
G
H
G
E
E
S
S
S
E
D
S
D
I
Rat
Rattus norvegicus
O54748
491
56103
R307
K
R
H
E
E
Q
Q
R
E
L
E
D
E
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513191
426
48196
S299
S
E
G
H
G
E
D
S
S
S
E
D
S
D
I
Chicken
Gallus gallus
Q5ZJK4
486
55318
R309
K
R
Q
E
A
Q
Q
R
E
L
D
Q
E
D
E
Frog
Xenopus laevis
Q6IP06
493
56486
R306
K
R
H
E
E
L
Q
R
E
L
E
E
E
D
E
Zebra Danio
Brachydanio rerio
Q7ZUQ3
492
56062
R306
K
R
Q
Q
E
Q
Q
R
E
L
E
E
D
D
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8T0S6
669
75091
F322
Q
Q
R
A
N
R
S
F
G
G
V
L
A
A
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9NB31
497
55620
A315
L
G
Q
A
P
M
A
A
S
S
G
N
D
A
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38692
1080
117043
Y305
R
D
K
N
K
N
K
Y
K
I
E
G
S
I
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
72.4
38.4
71.5
N.A.
98.5
38.4
N.A.
94.3
38.8
38.5
38.6
N.A.
29.7
N.A.
35.6
N.A.
Protein Similarity:
100
72.5
57
72.5
N.A.
99.7
55.1
N.A.
97.8
55.9
56.1
56.9
N.A.
42.1
N.A.
51.7
N.A.
P-Site Identity:
100
100
6.6
6.6
N.A.
100
13.3
N.A.
93.3
6.6
13.3
13.3
N.A.
0
N.A.
13.3
N.A.
P-Site Similarity:
100
100
26.6
20
N.A.
100
33.3
N.A.
100
26.6
26.6
33.3
N.A.
13.3
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
28.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
16
8
0
8
8
0
0
0
0
8
16
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
8
0
8
0
0
0
16
39
24
62
0
% D
% Glu:
0
39
0
31
24
31
24
0
39
0
62
16
31
8
39
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
8
31
0
31
0
0
0
8
8
8
8
0
8
0
% G
% His:
0
0
16
31
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
0
0
8
0
0
0
0
0
8
0
0
0
8
31
% I
% Lys:
39
0
8
0
8
0
8
8
8
0
8
0
0
0
0
% K
% Leu:
8
0
8
0
0
8
0
0
0
31
0
8
0
0
0
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
8
8
0
0
0
0
0
8
0
0
0
% N
% Pro:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
8
% P
% Gln:
8
8
31
8
0
31
39
0
0
0
0
16
0
0
0
% Q
% Arg:
8
39
8
0
0
16
0
39
8
0
0
0
0
0
0
% R
% Ser:
31
0
0
0
8
0
8
31
39
39
0
8
39
0
8
% S
% Thr:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% T
% Val:
0
0
0
0
0
0
0
0
0
8
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _